NEW BIODEGRADABLE BIOMEDICAL POLYMERS BASED ON SUCCINIC ACID

被引：4

作者：

Jaszcz, Katarzyna ^{[1
]}

Lukaszczyk, Jan ^{[1
]}

Smiga-Matuszowicz, Monika ^{[1
]}

机构：

[1] Politechn Slaska, Katedra Fizykochem & Technol Polimerow, PL-44100 Gliwice, Poland

来源：

POLIMERY | 2013年 / 58卷 / 09期

关键词：

succinic acid; functional polyesters; poly(ester-anhydride)s; biodegradable bone cements; microspheres; BONE-CEMENT COMPOSITIONS; IN-VITRO DEGRADATION; HYDROLYTIC DEGRADATION; POLY(PROPYLENE FUMARATE); BIONOLLE(R);

D O I：

10.14314/polimery.2013.670

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

A short review with 41 references on new functional polyesters and poly(ester-anhydride)s based on succinic acid is presented. The properties of poly(3-allyloxy-1,2-propylene succinate) and its possible use as a component of biodegradable bone cements are discussed. The methods for the oxidation of pendant allyl groups to other functional groups, including epoxy, with formation of polyester-epoxy resins potentially used in the preparation of biodegradable bone implants, are described. The second part of the article concerns various synthetic methods available for the preparation of poly(ester-anhydride)s based on oligo(3-allyloxy-1,2-propylene succinate). In order to obtain poly(ester-anhydride)s with different properties, various aliphatic dicarboxylic acids were employed in the syntheses. Also, the possibility of using selected poly(ester-anhydride)s for the construction of microsphere polymer-drug systems is discussed. The microspheres with porous structure can be used in controlled pulmonary drug delivery.

引用

页码：670 / 677

页数：8

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