Catalytic asymmetric ring opening of epoxides to chlorohydrins with mild chloride donors and enantiopure titanium complexes

被引：25

作者：

Bruns, S ^{[1
]}

Haufe, G ^{[1
]}

机构：

[1] Univ Munster, Inst Organ Chem, D-48149 Berlin, Germany

来源：

TETRAHEDRON-ASYMMETRY | 1999年 / 10卷 / 08期

关键词：

D O I：

10.1016/S0957-4166(99)00141-X

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The ring opening of symmetric and racemic epoxides with dilithium tetrachlorocuprate or trimethylsilyl chloride in the presence of titanium (R,R)-(+)-TADDOLates or a titanium (R)-(+)-BINOL complex gave vicinal chlorohydrins or their TMS ethers with maximum 36% enantiomeric excess. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：1563 / 1569

页数：7

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[3]

2-A

[4]

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