Cold atmospheric plasma: Charged species and their interactions with cells and tissues

被引:415
作者
Stoffels, Eva [1 ]
Sakiyama, Yukinori [2 ]
Graves, David B. [2 ]
机构
[1] Eindhoven Univ Technol, Fac Biomed Engn, NL-5600 Eindhoven, Netherlands
[2] Univ Calif Berkeley, Dept Chem Engn, Berkeley, CA 94720 USA
关键词
cold atmospheric plasma (CAP); plasma medicine; surface treatment;
D O I
10.1109/TPS.2008.2001084
中图分类号
O35 [流体力学]; O53 [等离子体物理学];
学科分类号
070204 ; 080103 ; 080704 ;
摘要
Cold atmospheric plasma (CAP) treatment of living tissues becomes a popular topic in modern plasma physics and in medical sciences. The plasma is capable of bacterial inactivation and noninflammatory tissue modification, which makes it an attractive tool for wound healing and the treatment of skin diseases and dental caries. There are still many open issues with regard to the mechanisms of action of the plasma on bacteria and mammalian cells and tissues, both from the biological and the physical perspective. For example, the chemistry of CAP and the exact roles of various plasma constituents in tissue treatment are not yet fully resolved. In this paper, we shall concentrate on the charged species (electrons and ions) in the plasma. The selected physical properties of typical atmospheric plasma sources will be discussed; experiments will be confronted with theoretical considerations, and several biomedical aspects of CAP treatment will be surveyed.
引用
收藏
页码:1441 / 1457
页数:17
相关论文
共 86 条
[1]   Biofilm destruction by RF high-pressure cold plasma jet [J].
Abramzon, Nina ;
Joaquin, Jonathan C. ;
Bray, Jonathan ;
Brelles-Marino, Graciela .
IEEE TRANSACTIONS ON PLASMA SCIENCE, 2006, 34 (04) :1304-1309
[2]  
Alberts B., 1994, MOL BIOL CELL
[3]  
[Anonymous], 2001, INTRO DUSTY PLASMA P
[4]  
ARANDAGONZALVO Y, 2006, J VAC SCI TECHNOL A, V24, P550
[5]   Application of a flocculation-ultrafiltration process for bacteria (Desulfovibrio desulfuricans) removal from industrial plant process water [J].
Bayat, O ;
Arslan, V ;
Bayat, B ;
Poole, C .
BIOCHEMICAL ENGINEERING JOURNAL, 2004, 18 (02) :105-110
[6]  
Becker K.H., 2004, SERIES PLASMA PHYS
[7]   INDUCTION OF A COMMON PATHWAY OF APOPTOSIS BY STAUROSPORINE [J].
BERTRAND, R ;
SOLARY, E ;
OCONNOR, P ;
KOHN, KW ;
POMMIER, Y .
EXPERIMENTAL CELL RESEARCH, 1994, 211 (02) :314-321
[8]   Multi-scale simulation of functionalization of rough polymer surfaces using atmospheric pressure plasmas [J].
Bhoj, AN ;
Kushner, MJ .
JOURNAL OF PHYSICS D-APPLIED PHYSICS, 2006, 39 (08) :1594-1598
[9]   Antimicrobial treatment of heat sensitive materials by means of atmospheric pressure rf-driven plasma jet [J].
Brandenburg, R. ;
Ehlbeck, J. ;
Stieber, M. ;
von Woedtke, T. ;
Zeymer, J. ;
Schlueter, O. ;
Weltmann, K. -D. .
CONTRIBUTIONS TO PLASMA PHYSICS, 2007, 47 (1-2) :72-79
[10]   Numerical description of discharge characteristics of the plasma needle [J].
Brok, WJM ;
Bowden, MD ;
van Dijk, J ;
van der Mullen, JJAM ;
Kroesen, GMW .
JOURNAL OF APPLIED PHYSICS, 2005, 98 (01)