Disseminated Aspergillosis in the Immunocompetent Host: A Case Report and Literature Review

被引:11
作者
Cheon, Shinhye [1 ,2 ]
Yang, Min Kyu [3 ]
Kim, Chung-Jong [1 ,2 ]
Kim, Taek Soo [4 ]
Song, Kyoung-Ho [1 ,2 ]
Woo, Se Joon [3 ]
Kim, Eu Suk [1 ,2 ]
Park, Kyoung Un [4 ]
Kim, Hong Bin [1 ,2 ]
机构
[1] Seoul Natl Univ, Bundang Hosp, Dept Internal Med, Songnam 463707, Gyeonggi Do, South Korea
[2] Seoul Natl Univ, Coll Med, Dept Internal Med, Seoul 151, South Korea
[3] Seoul Natl Univ, Bundang Hosp, Dept Ophthalmol, Songnam, South Korea
[4] Seoul Natl Univ, Bundang Hosp, Dept Lab Med, Songnam, South Korea
关键词
Immunocompetent host; Disseminated aspergillosis; Endophthalmitis; Spondylitis; PULMONARY ASPERGILLOSIS; ENDOPHTHALMITIS; DIAGNOSIS;
D O I
10.1007/s11046-015-9903-4
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Disseminated aspergillosis is very rare in immunocompetent hosts and is typically associated with a poor prognosis. We describe the case of a 66-year-old, immunocompetent man who developed pneumonia, endophthalmitis and probable spondylitis caused by Aspergillus species. The patient was successfully treated with antifungal drugs. We reviewed the English-language literature between 1980 and 2012 for disseminated aspergillosis cases in immunocompetent hosts, using the keywords "dissemin*" and "aspergillo*." Disseminated aspergillosis in immunocompetent hosts is very rare in the literature. However, awareness of possible dissemination of Aspergillus spp. is necessary in patients who have a probable lung lesion and in cases with unusual presentation of a disseminated infection, even if the patient has no risk factors.
引用
收藏
页码:217 / 222
页数:6
相关论文
共 15 条
  • [1] CHRONIC NECROTIZING PULMONARY ASPERGILLOSIS - A DISCRETE CLINICAL ENTITY
    BINDER, RE
    FALING, LJ
    PUGATCH, RD
    MAHASAEN, C
    SNIDER, GL
    [J]. MEDICINE, 1982, 61 (02) : 109 - 123
  • [2] DISSEMINATED ASPERGILLOSIS IN AN APPARENTLY HEALTHY PATIENT
    COOK, DJ
    ACHONG, MR
    KING, DEL
    [J]. AMERICAN JOURNAL OF MEDICINE, 1990, 88 (01) : 74 - 76
  • [3] Invasive aspergillosis
    Denning, DW
    [J]. CLINICAL INFECTIOUS DISEASES, 1998, 26 (04) : 781 - 803
  • [4] SEMI-INVASIVE PULMONARY ASPERGILLOSIS - A NEW LOOK AT THE SPECTRUM OF ASPERGILLUS INFECTIONS OF THE LUNG
    GEFTER, WB
    WEINGRAD, TR
    EPSTEIN, DM
    OCHS, RH
    MILLER, WT
    [J]. RADIOLOGY, 1981, 140 (02) : 313 - 321
  • [5] Risk stratification for invasive aspergillosis in immunocompromised patients
    Herbrecht, Raoul
    Bories, Pierre
    Moulin, Jean-Charles
    Ledoux, Marie-Pierre
    Letscher-Bru, Valerie
    [J]. ADVANCES AGAINST ASPERGILLOSIS I, 2012, 1272 : 23 - 30
  • [6] Trends in the postmortem epidemiology of invasive fungal infections at a university hospital
    Lehrnbecher, T.
    Frank, C.
    Engels, K.
    Kriener, S.
    Groll, A. H.
    Schwabe, D.
    [J]. JOURNAL OF INFECTION, 2010, 61 (03) : 259 - 265
  • [7] Logan Sa, 2010, Cases J, V3, P31, DOI 10.1186/1757-1626-3-31
  • [8] Manandhar A, 2012, NEPAL J OPHTHALMOL, V4, P179, DOI 10.3126/nepjoph.v4i1.5873
  • [9] Myles WM, 1997, CAN J OPHTHALMOL, V32, P182
  • [10] Orem J, 1998, E AFR MED J, V75, P436