Solvent-free aryl amination catalysed by [Pd(NHC)] complexes

被引：60

作者：

Chartoire, Anthony ^{[1
]}

Boreux, Arnaud ^{[1
]}

Martin, Anthony R. ^{[1
]}

Nolan, Steven P. ^{[1
]}

机构：

[1] Univ St Andrews, EaStCHEM Sch Chem, St Andrews KY16 9ST, Fife, Scotland

来源：

RSC ADVANCES | 2013年 / 3卷 / 12期

关键词：

N-HETEROCYCLIC CARBENE; CROSS-COUPLING REACTIONS; SUZUKI-MIYAURA; ARYLBORONIC ACIDS; BUCHWALD-HARTWIG; BOND FORMATION; PRE-CATALYST; C-N; EFFICIENT; PRECATALYST;

D O I：

10.1039/c3ra40386f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A highly effective solvent-free protocol for the Buchwald-Hartwig amination of unactivated aryl chlorides is described. The effect of various [Pd(NHC)] pre-catalyst systems on the reactivity has been studied. [Pd(IPr*)(cin)Cl] is reported as the complex of choice for the transformation.

引用

页码：3840 / 3843

页数：4

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