A Simple Paper-Based Microfluidic Device for the Determination of the Total Amino Acid Content in a Tea Leaf Extract

被引：61

作者：

Cai, Longfei ^{[1
]}

Wu, Yunying ^{[1
]}

Xu, Chunxiu ^{[1
]}

Chen, Zefeng ^{[1
]}

机构：

[1] Hanshan Normal Univ, Dept Chem, Chaozhou 521041, Guangdong, Peoples R China

来源：

JOURNAL OF CHEMICAL EDUCATION | 2013年 / 90卷 / 02期

关键词：

Second-Year Undergraduate; Analytical Chemistry; Laboratory Instruction; Hands-On Learning/Manipulatives; Amino Acids; Applications of Chemistry; Food Science; Laboratory Equipment/Apparatus; Microscale Lab; Quantitative Analysis; CHIPS; ASSAY;

D O I：

10.1021/ed300385j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An experiment was developed to demonstrate a microfluidic device in the analytical chemistry (instrumental analysis) laboratory. Students made the paper-based microfluidic device with a wax pen and a piece of filter paper and used it to determine the total quantity of amino acids in a green tea leaf extract. The device is low cost, easy-to-make, and easy-to-use. The student results compared favorably with those from standard method.

引用

页码：232 / 234

页数：3

共 25 条

[1] Microfluidics-based systems biology [J].

Breslauer, DN ;

Lee, PJ ;

Lee, LP .

MOLECULAR BIOSYSTEMS, 2006, 2 (02) :97-112

[2] Droplet-Based Microfluidic Flow Injection System with Large-Scale Concentration Gradient by a Single Nanoliter-Scale Injection for Enzyme Inhibition Assay [J].

Cai, Long-Fei ;

Zhu, Ying ;

Du, Guan-Sheng ;

Fang, Qun .

ANALYTICAL CHEMISTRY, 2012, 84 (01) :446-452

[3] Chemistry in Microfluidic Channels [J].

Chia, Matthew C. ;

Sweeney, Christina M. ;

Odom, Ted W. .

JOURNAL OF CHEMICAL EDUCATION, 2011, 88 (04) :461-464

[4] Use of multiple colorimetric indicators for paper-based microfluidic devices [J].

Dungchai, Wijitar ;

Chailapakul, Orawon ;

Henry, Charles S. .

ANALYTICA CHIMICA ACTA, 2010, 674 (02) :227-233

[5] Education: A modular approach to microfluidics in the teaching laboratory [J].

Fintschenko, Yolanda .

LAB ON A CHIP, 2011, 11 (20) :3394-3400

[6] Microchip device for performing enzyme assays [J].

Hadd, AG ;

Raymond, DE ;

Halliwell, JW ;

Jacobson, SC ;

Ramsey, JM .

ANALYTICAL CHEMISTRY, 1997, 69 (17) :3407-3412

[7] Multistep Microchemical Synthesis Enabled by Microfluidic Distillation [J].

Hartman, Ryan L. ;

Naber, John R. ;

Buchwald, Stephen L. ;

Jensen, Klavs F. .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, 49 (05) :899-903

[8] Bonding of glass microfluidic chips at room temperatures [J].

Jia, ZJ ;

Fang, Q ;

Fang, ZL .

ANALYTICAL CHEMISTRY, 2004, 76 (18) :5597-5602

[9] Development of a Paper-Based Analytical Device for Colorimetric Detection of Select Foodborne Pathogens [J].

Jokerst, Jana C. ;

Adkins, Jaclyn A. ;

Bisha, Bledar ;

Mentele, Mallory M. ;

Goodridge, Lawrence D. ;

Henry, Charles S. .

ANALYTICAL CHEMISTRY, 2012, 84 (06) :2900-2907

[10] Paper-based microfluidic devices for analysis of clinically relevant analytes present in urine and saliva [J].

Klasner, Scott A. ;

Price, Alexander K. ;

Hoeman, Kurt W. ;

Wilson, Rashaun S. ;

Bell, Kayla J. ;

Culbertson, Christopher T. .

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2010, 397 (05) :1821-1829

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