Nickel-mediated coupling reactions of carboryne with alkenes: A synthetic route to alkenylcarboranes

被引：40
|
作者：
Qiu, Zaozao
Xie, Zuowei [1 ]
机构：
[1] Chinese Univ Hong Kong, Dept Chem, Shatin, Hong Kong, Peoples R China
[2] Chinese Univ Hong Kong, Ctr Novel Funct Mol, Shatin, Hong Kong, Peoples R China
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 35期
关键词：
alkenes; C-C coupling; carboranes; metalation; nickel;
D O I：
10.1002/anie.200801958
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Happily coupled: A nickel-carboryne complex 1 reacts with substituted styrenes 2 to afford alkenylcarboranes in moderate to very good yields with excellent regio- and steroselectivity. Either the "Heck-type" (3) or the "ene-reaction-type" product (4) could be isolated (see scheme). A reaction mechanism that involves alkene insertion followed by successive β-H elimination and reductive elimination steps is proposed. (Chemical Equation Presented). © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码：6572 / 6575
页数：4
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