Antimicrobial activity of clove oil and its potential in the treatment of vaginal candidiasis

被引：41
作者：
Ahmad, N
Alam, MK
Shehbaz, A
Khan, A
Mannan, A
Hakim, SR
Bisht, D
Owais, M [1 ]
机构：
[1] Aligarh Muslim Univ, Interdisciplinary Biotechnol Unit, Aligarh 202002, Uttar Pradesh, India
[2] Jamia Hamdard, Fac Pharm, New Delhi, India
[3] Aligarh Muslim Univ, Tibbiya Coll, HAK, Aligarh 202002, Uttar Pradesh, India
[4] Aligarh Muslim Univ, JN Med Coll, Aligarh 202002, Uttar Pradesh, India
[5] JALMA Leprosy Inst, Agra, Uttar Pradesh, India
来源：
JOURNAL OF DRUG TARGETING | 2005年 / 13卷 / 10期
关键词：
clove oil; liposome; vaginal candidiasis; Candida; nystatin; essential oil;
D O I：
10.1080/10611860500422958
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
In the present study, we evaluated antimicrobial activity of clove oil against a range of fungal pathogens including that responsible for urogenital infection. Clove oil was found to possess strong antifungal activity against opportunistic fungal pathogens such as Candida albicans , Cryptococcus neoformans and Aspergillus fumigatus , etc. The oil was found to be extremely successful in the treatment of experimental murine vaginitis in model animals. On evaluating various formulations, topical administration of the liposomized clove oil was found to be most effective against treatment of vaginal candidiasis.
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收藏
页码：555 / 561
页数：7
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