STEM CELLS Reprogramming in situ

被引:6
作者
De Los Angeles, Alejandro [1 ,2 ,3 ,4 ]
Daley, George Q. [1 ,2 ,3 ,4 ]
机构
[1] Childrens Hosp, Div Pediat Hematol & Oncol, Stem Cell Transplantat Program, Boston, MA 02115 USA
[2] Dana Farber Canc Inst, Boston, MA 02115 USA
[3] Harvard Univ, Sch Med, Howard Hughes Med Inst, Harvard Stem Cell Inst, Boston, MA 02115 USA
[4] Harvard Univ, Sch Med, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA
关键词
DIFFERENTIATION; PLURIPOTENCY;
D O I
10.1038/nature12559
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Cellular reprogramming to a stem-cell state has now been achieved in tissues of genetically engineered mice. This work signals a future for regenerative medicine in which tissue fates might be manipulated in living organisms. See Article p.340
引用
收藏
页码:309 / 310
页数:2
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