An efficient method for synthesis of α-keto acid esters from terminal alkynes

被引：54

作者：

Li, LS ^{[1
]}

Wu, YL ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Bioorgan & Nat Prod Chem, Shanghai 200032, Peoples R China

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 13期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.1016/S0040-4039(02)00290-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

alpha-Keto acid esters can be easily prepared in high yields in two steps from terminal alkynes via bromination and oxidation. This strategy provides a versatile access to the synthesis of biologically important natural products with an alpha-keto acid moiety. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：2427 / 2430

页数：4

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