Ent-3,4-seco-labdane and ent-labdane diterpenoids from Croton stipuliformis (Euphorbiaceae)

被引：19

作者：

Ramos, Freddy ^{[1
,2
]}

Takaishi, Yoshihisa ^{[2
]}

Kashiwada, Yoshiki ^{[2
]}

Osorio, Coralia ^{[1
]}

Duque, Carmenza ^{[1
]}

Acuna, Ricardo ^{[3
]}

Fujimoto, Yoshinori ^{[4
]}

机构：

[1] Univ Nacl Colombia, Dept Quim, Bogota 14490, Colombia

[2] Univ Tokushima, Grad Sch Pharmaceut Sci, Tokushima 7708505, Japan

[3] Ctr Nacl Invest Cafe, Planalto Chinchina, Colombia

[4] Tokyo Inst Technol, Dept Chem & Mat Sci, Meguro Ku, Tokyo 1528551, Japan

来源：

PHYTOCHEMISTRY | 2008年 / 69卷 / 12期

关键词：

Croton stiputiformis; euphorbiaceae; ent-labdane; ent-3,4-seco-labdanes; ent-3.4-seco-15-nor-labdanes; absolute configuration;

D O I：

10.1016/j.phytochem.2008.05.025

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

From a methanolic extract of the leaves of Croton stipuliformis, three ent-3,4-seco-labdanes (1-3) and an ent-labdane (4) together with the known compounds 6-hydroxynidorellol (5), maravuic acid, and sitosterol were isolated and identified from their spectroscopic data. The absolute stereochemistry of compound 4 was determined by application of Mosher's method in the NMR tube. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：2406 / 2410

页数：5

共 14 条

[1] Seco diterpenoids from Excoecaria agallocha L. [J].

Anjaneyulu, ASR ;

Rao, VL .

PHYTOCHEMISTRY, 2003, 62 (04) :585-589

[2] NEW DITERPENES AND ACETYLENIC-COMPOUNDS FROM NIDORELLA SPECIES [J].

BOHLMANN, F ;

FRITZ, U .

PHYTOCHEMISTRY, 1978, 17 (10) :1769-1772

[3] LABDANE DITERPENOIDS FROM STEVIA-SELERIANA [J].

ESCAMILLA, EM ;

ORTEGA, A .

PHYTOCHEMISTRY, 1991, 30 (02) :599-602

[4] NEW DITERPENES FROM CHILIOTRICHIUM-ROSMARINIFOLIUM AND NARDOPHYLLUM-LANATUM [J].

JAKUPOVIC, J ;

BANERJEE, S ;

BOHLMANN, F ;

KING, RM ;

ROBINSON, H .

TETRAHEDRON, 1986, 42 (05) :1305-1313

[5]

KOBAYASHI M, 1991, CHEM PHARM BULL, V39, P3348, DOI 10.1248/cpb.39.3348

[6] PHOTOSENSITIZED OXYGENATION OF LABDA-8(17),12-DIENE, LABDA-8(17),13-DIENE, AND THE BIFORMENES - SYNTHESIS OF PUMILOXIDE [J].

MOHANRAJ, S ;

HERZ, W .

JOURNAL OF ORGANIC CHEMISTRY, 1981, 46 (07) :1362-1366

[7]

Murillo J., 2004, BIOTA COLOMBIANA, V5, P183

[8] HIGH-FIELD FT NMR APPLICATION OF MOSHER METHOD - THE ABSOLUTE-CONFIGURATIONS OF MARINE TERPENOIDS [J].

OHTANI, I ;

KUSUMI, T ;

KASHMAN, Y ;

KAKISAWA, H .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1991, 113 (11) :4092-4096

[9] Isolation of austroinulin possessing cell cycle inhibition activity from Blumea glomerata and revision of its absolute configuration [J].

Ohtsuki, T ;

Koyano, T ;

Kowithayakorn, T ;

Yamaguchi, N ;

Ishibashi, M .

PLANTA MEDICA, 2004, 70 (12) :1170-1173

[10]

Palazzino G, 1997, GAZZ CHIM ITAL, V127, P311

← 1 2 →