Exceptional response to brivaracetam in a patient with refractory idiopathic generalized epilepsy and absence seizures

被引：10

作者：

Grande-Martin, Alberto ^{[1
,2
]}

Sopelana-Garay, David ^{[1
]}

Manuel Pardal-Fernandez, Jose ^{[2
]}

Maria Sanchez-Honrubia, Rosa ^{[2
]}

Abelardo Sanchez-Larsen, Alvaro ^{[1
]}

机构：

[1] Gen Hosp Albacete, Dept Neurol, Albacete, Spain

[2] Gen Hosp Albacete, Dept Clin Neurophysiol, Albacete, Spain

来源：

EPILEPTIC DISORDERS | 2018年 / 20卷 / 01期

关键词：

antiepileptic drug; brivaracetam; idiopathic generalized epilepsy; absence seizure; EEG; DOUBLE-BLIND; LIGAND; SV2A;

D O I：

10.1684/epd.2017.0939

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Brivaracetam is currently indicated as adjunctive therapy for patients with focal-onset seizures with or without secondary generalization. However, it has been suggested that it could provide broad-spectrum efficacy given its similarity to levetiracetam and based on the results from preclinical studies and others of patients with generalized epilepsy. We present the case of awoman with refractory idiopathic generalized epilepsy and absence seizures with dramatic response to brivaracetam. Our report supports a consideration of treatment with this new antiepileptic drug on a case-by-case basis in patients with refractory generalized epilepsy, while we await further studies on this topic.

引用

页码：60 / 64

页数：5

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