3D Printing of Multifunctional Hydrogels

被引：317

作者：

Chen, Zhe ^{[1
,2
]}

Zhao, Donghao ^{[1
,2
]}

Liu, Binhong ^{[1
,2
]}

Nian, Guodong ^{[1
,2
]}

Li, Xiaokeng ^{[2
,3
]}

Yin, Jun ^{[2
,3
]}

Qu, Shaoxing ^{[1
,2
]}

Yang, Wei ^{[1
]}

机构：

[1] Zhejiang Univ, Key Lab Soft Machines & Smart Devices Zhejiang Pr, Ctr X Mech, Dept Engn Mech, Hangzhou 310027, Zhejiang, Peoples R China

[2] Zhejiang Univ, State Key Lab Fluid Power & Mechatron Syst, Hangzhou 310027, Zhejiang, Peoples R China

[3] Zhejiang Univ, Key Lab 3D Printing Proc & Equipment Zhejiang Pro, Sch Mech Engn, Hangzhou 310027, Zhejiang, Peoples R China

来源：

ADVANCED FUNCTIONAL MATERIALS | 2019年 / 29卷 / 20期

基金：

中国国家自然科学基金;

关键词：

3D printing; bioprinting; multifunctional hydrogels; rheology modifier; soft devices; DRUG-DELIVERY; TRANSPARENT; SCAFFOLDS; TOUGHNESS; STRENGTH; CARBOMER; COMPLEX;

D O I：

10.1002/adfm.201900971

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

3D printing technology has been widely explored for the rapid design and fabrication of hydrogels, as required by complicated soft structures and devices. Here, a new 3D printing method is presented based on the rheology modifier of Carbomer for direct ink writing of various functional hydrogels. Carbomer is shown to be highly efficient in providing ideal rheological behaviors for multifunctional hydrogel inks, including double network hydrogels, magnetic hydrogels, temperature-sensitive hydrogels, and biogels, with a low dosage (at least 0.5% w/v) recorded. Besides the excellent printing performance, mechanical behaviors, and biocompatibility, the 3D printed multifunctional hydrogels enable various soft devices, including loadable webs, soft robots, 4D printed leaves, and hydrogel Petri dishes. Moreover, with its unprecedented capability, the Carbomer-based 3D printing method opens new avenues for bioprinting manufacturing and integrated hydrogel devices.

引用

页数：8

共 45 条

[1] Direct-Write Assembly of 3D Hydrogel Scaffolds for Guided Cell Growth [J].