Vinylcyclopropane Derivatives in Transition-Metal-Catalyzed Cycloadditions for the Synthesis of Carbocyclic Compounds

被引：279

作者：

Jiao, Lei ^{[1
]}

Yu, Zhi-Xiang ^{[1
]}

机构：

[1] Peking Univ, Coll Chem, Beijing 100871, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2013年 / 78卷 / 14期

基金：

中国国家自然科学基金;

关键词：

INTRAMOLECULAR 5+2 CYCLOADDITIONS; RH(I)-CATALYZED (5+2)+1 CYCLOADDITION; ASYMMETRIC TOTAL-SYNTHESIS; DENSITY-FUNCTIONAL THEORY; NATURAL-PRODUCT SYNTHESIS; DIELS-ALDER REACTION; ENE-VINYLCYCLOPROPANES; VINYL-CYCLOPROPANES; 7-MEMBERED RINGS; ENANTIOSELECTIVE SYNTHESIS;

D O I：

10.1021/jo400609w

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Vinylcyclopropane (VCP) derivatives participate in a variety of transition-metal-catalyzed multicomponent cycloadditions to produce five- to eight-membered carbocycles. Various cycloaddition modes provide novel approaches to mono-, bi-, and polycyclic molecules. In this Synopsis, recent advances in transition-metal-catalyzed VCP cycloadditions are discussed, with a particular emphasis on the influence of VCP substitution pattern on cycloaddition modes. A tabular summary of applications of the VCP cycloadditions in natural product synthesis is also presented.

引用

页码：6842 / 6848

页数：7

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