Prognosis in Women with Breast Cancer and Private Extra Insurance Coverage

被引:7
作者
Grau, Juan J. [1 ]
Zanon, Gabriel [1 ]
Caso, Carlos [2 ]
Gonzalez, Xavier [1 ]
Rodriguez, Araceli [2 ]
Caballero, Miguel [3 ]
Biete, Albert [1 ]
机构
[1] Univ Barcelona, Fac Med, Dept Clin Oncol, Barcelona 7, Spain
[2] Clin Sagrada Familia, Gynecol & Reprod Serv, Barcelona, Spain
[3] Univ Barcelona, Dept Surg, IDIBAPS Augusto Pi & Sunyer Mem Inst Biomed Res, Barcelona, Spain
关键词
RANDOMIZED-TRIAL; ADJUVANT CHEMOTHERAPY; POSTMENOPAUSAL WOMEN; TAMOXIFEN THERAPY; STAGE; COMBINATION; DOXORUBICIN; DIAGNOSIS; DOCETAXEL;
D O I
10.1245/s10434-013-3025-3
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Many women covered by the Spanish public health system also have an extra private insurance policy for gynecological examinations and routine annual mammography. We retrospectively analyzed the long-term survival rates in these patients when diagnosed with breast cancer. We analyzed the survival and prognostic factors in patients diagnosed with breast cancer who were referred to a medical oncology unit for multidisciplinary treatment covered by private health insurance. Between 1994 and 2009, a total of 434 patients with breast tumor were analyzed: 33 in situ and 401 infiltrating. Among the infiltrating carcinomas, 38 were stage IV and 363 were stage I, II, or III. With a median follow-up of 62 months, the 5-year global survival rate was 91 %: 97 % for stage I, 94 % for stage II, and 77 % for stage III tumors. In the patients diagnosed by routine mammography, the 5-year survival rate was 96 %, compared with 86 % in those consulting their gynecologist after breast self-examination or for other symptoms (p = 0.0159). Seventy-four percent were treated conservatively and experienced better survival than the 26 % who underwent mastectomy (p = 0.0024). Patients with disease with positive hormone receptors had a better survival rate (p = 0.0264); hormone receptor status was the only independent prognostic factor in the Cox multivariate analysis. Postmenopausal patients who received adjuvant tamoxifen plus exemestane had a better prognosis than those who received tamoxifen alone (p = 0.0203). Long-term survival rate was high in breast cancer patients with extra private insurance coverage. This is probably because disease was diagnosed at an early stage.
引用
收藏
页码:2822 / 2827
页数:6
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