Palladium-Catalyzed Regiodivergent Substitution of Propargylic Carbonates

被引：43
作者：
Locascio, Theresa M. [1 ]
Tunge, Jon A. [1 ]
机构：
[1] Univ Kansas, Dept Chem, 2010 Malott Hall,1251 Wescoe Hall Dr, Lawrence, KS 66045 USA
来源：
CHEMISTRY-A EUROPEAN JOURNAL | 2016年 / 22卷 / 50期
基金：
美国国家科学基金会;
关键词：
coupling; dienylation; palladium; propargylation; CROSS-COUPLING REACTIONS; STEREOSELECTIVE-SYNTHESIS; SELECTIVE SYNTHESIS; NUCLEOPHILIC-SUBSTITUTION; CYCLIZATION REACTIONS; ASYMMETRIC-SYNTHESIS; CASCADE REACTIONS; ALLYL; DERIVATIVES; COMPLEXES;
D O I：
10.1002/chem.201603481
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The palladium(0)-catalyzed, ligand-controlled, regioselective addition of diaryl acetonitrile pronucleophiles to propargylic carbonates is reported. Selective formation of either terminal 1,3-dienyl or propargylated products is proposed to arise from a change in reaction mechanism controlled by the denticity of the coordinating ligand.
引用
收藏
页码：18140 / 18146
页数：7
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