Novel functions of type I interferons revealed by infection studies with Listeria monocytogenes

被引:28
|
作者
Stockinger, Silvia [1 ]
Decker, Thomas [1 ]
机构
[1] Univ Vienna, Dept Microbiol & Immunobiol, Max F Perutz Labs, A-1030 Vienna, Austria
基金
奥地利科学基金会;
关键词
Infection; Intracellular bacteria; Listeria monocytogenes; Type I interferons; TLR;
D O I
10.1016/j.imbio.2008.07.020
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Infection of cells and mice with Listeria monocytogenes stimulates production of type I interferons (IFN). These in turn sensitise the Listeria host to lethal sequelae of infection with these bacteria. Here, we summarise recent findings on the production and biological effects of type I IFN in the course of L. monocytogenes infection. (C) 2008 Elsevier GmbH. All rights reserved.
引用
收藏
页码:889 / 897
页数:9
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