Renal function overestimation in underweight and/or non-ambulatory patients

被引：3

作者：

Keshavarzi, Fazlollah ^{[1
]}

机构：

[1] UCSI Univ, Kuala Lumpur, Malaysia

来源：

INTERNATIONAL JOURNAL OF CLINICAL PHARMACY | 2015年 / 37卷 / 05期

关键词：

Bed-confined; Creatinine clearance; Cystatin C; Renal function overestimation; Underweight patients; ESTIMATING CREATININE CLEARANCE; SERUM CYSTATIN-C; PREDICTION;

D O I：

10.1007/s11096-015-0157-5

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Creatinine clearance estimation is widely used to evaluate the renal function of the patients in order to initiate or adjust the drugs dosage. However serum creatinine, as a muscle metabolism by-product, may not be a reliable parameter in underweight and/or non-ambulatory patients, such as geriatric, acquired immunodeficiency syndrome patients and bed-confined and cachexic cases. To avoid overestimation of the renal function in those patients, serum cystatin C can be considered as a sensitive and accurate alternative for serum creatinine.

引用

收藏

页码：675 / 677

页数：3

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