THE BILE ACID RECEPTOR TGR5 PROMOTES CHOLANGIOCYTE PROLIFERATION THROUGH A cSRC-EGFR-ERK SIGNALLING PATHWAY

被引：2
|
作者：
Keitel, V. [1 ]
Reich, M. [1 ]
Sommerfeld, A. [1 ]
Kluge, S. [1 ]
Kubitz, R. [1 ]
Haeussinger, D. [1 ]
机构：
[1] Univ Hosp Dusseldorf, Dusseldorf, Germany
来源：
JOURNAL OF HEPATOLOGY | 2013年 / 58卷
关键词：
D O I：
10.1016/S0168-8278(13)61426-9
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
1427
引用
收藏
页码：S574 / S575
页数：2
相关论文
共 50 条
  • [1] Activation of the bile acid receptor TGR5 (Gpbar-1) induces cholangiocyte proliferation through a ROS-Src-EGFR-ERK signalling pathway
    Keitel, Verena
    Reich, Maria
    Sommerfeld, Annika
    Kluge, Stefanie
    Kubitz, Ralf
    Haeussinger, Dieter
    HEPATOLOGY, 2013, 58 : 846A - 846A
  • [2] TGR5 SIGNALLING IS ESSENTIAL FOR BILE ACID-DEPENDENT CHOLANGIOCYTE PROLIFERATION IN VIVO
    Reich, M. K.
    Deutschmann, K.
    Klindt, C.
    Herebian, D.
    Mayatepek, E.
    Haeussinger, D.
    Keitel, V.
    JOURNAL OF HEPATOLOGY, 2016, 64 : S348 - S348
  • [3] Cholangiocyte proliferation induced by bile acids: impact of TGR5
    Barichon, Caroline
    Correia, Caroline
    Tordjmann, Thierry
    M S-MEDECINE SCIENCES, 2016, 32 (6-7): : 585 - 587
  • [4] TGR5 is essential for bile acid-dependent cholangiocyte proliferation in vivo and in vitro
    Reich, Maria
    Deutschmann, Kathleen
    Sommerfeld, Annika
    Klindt, Caroline
    Kluge, Stefanie
    Kubitz, Ralf
    Ullmer, Christoph
    Knoefel, Wolfram T.
    Herebian, Diran
    Mayatepek, Ertan
    Haeussinger, Dieter
    Keitel, Verena
    GUT, 2016, 65 (03) : 487 - 501
  • [5] The role of bile acid receptor TGR5 in regulating inflammatory signalling
    Ye, Daijiao
    He, Jiayao
    He, Xiaofei
    SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2024, 99 (04)
  • [6] STIMULATION OF THE BILE ACID RECEPTOR TGR5 PROMOTES INTESTINAL GROWTH
    Hunt, Jenna
    Hartmann, Bolette
    Ullmer, Christoph
    Holst, Jens J.
    Kissow, Hannelouise
    GASTROENTEROLOGY, 2018, 154 (06) : S333 - S333
  • [7] Bile acid–TGR5 axis promotes beiging
    Conor A. Bradley
    Nature Reviews Endocrinology, 2018, 14 : 130 - 130
  • [8] Hepatoprotective impact of the bile acid receptor TGR5
    Merlen, Gregory
    Bidault-Jourdainne, Valeska
    Kahale, Nicolas
    Glenisson, Mathilde
    Ursic-Bedoya, Jose
    Doignon, Isabelle
    Garcin, Isabelle
    Humbert, Lydie
    Rainteau, Dominique
    Tordjmann, Thierry
    LIVER INTERNATIONAL, 2020, 40 (05) : 1005 - 1015
  • [9] The Bile Acid Receptor TGR5 and Liver Regeneration
    Jourdainne, Valeska
    Pean, Noemie
    Doignon, Isabelle
    Humbert, Lydie
    Rainteau, Dominique
    Tordjmann, Thierry
    DIGESTIVE DISEASES, 2015, 33 (03) : 319 - 326
  • [10] Lithocholic acid promotes skeletal muscle regeneration through the TGR5 receptor
    Sun, Lijuan
    Li, Fan
    Tan, Weihao
    Zhao, Weijie
    Li, Yongxiang
    Zhu, Xiaotong
    Gao, Ping
    Shu, Gang
    Wang, Songbo
    Jiang, Qingyan
    Wang, Lina
    ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2023, 55 (01): : 51 - 61
12345