Can a Direct IADL Measure Detect Deficits in Persons with MCI?

被引：23

作者：

Binegar, Dani L. ^{[1
]}

Hynan, Linda S. ^{[1
,2
]}

Lacritz, Laura H. ^{[1
,3
]}

Weiner, Myron F. ^{[1
,3
]}

Cullum, C. Munro ^{[1
,3
]}

机构：

[1] Univ Texas SW Med Ctr Dallas, Dept Psychiat, Dallas, TX 75390 USA

[2] Univ Texas SW Med Ctr Dallas, Dept Clin Sci Biostat, Dallas, TX 75390 USA

[3] Univ Texas SW Med Ctr Dallas, Dept Neurol, Dallas, TX 75390 USA

来源：

CURRENT ALZHEIMER RESEARCH | 2009年 / 6卷 / 01期

关键词：

Mild cognitive impairment; IADL; Texas Functional Living Scale; MILD-COGNITIVE-IMPAIRMENT; ALZHEIMERS-DISEASE; COMPLEX ACTIVITIES; DEMENTIA; INSTRUMENT; ABILITIES; CAPACITY; SCALE;

D O I：

10.2174/156720509787313880

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Objective: To determine if a direct measure of instrumental activities of daily living (IADL) scale designed for use with dementia patients can detect differences between persons with mild cognitive impairment (MCI) and normal elderly control subjects (NC). Methods: This study used cross-sectional and longitudinal IADL scale data from MCI and NC subjects followed at an Alzheimer's Disease Center. Results: On a 52-point scale, MCI subjects (n = 30) scored significantly lower than NC subjects (n = 30) on the IADL scale (total score 47.17 vs. 48.77 points; t (58) = 2.34, p = .011) and its Memory subscale (5.27 vs. 6.6 points; t (58) = 3.29, p = .002). Examination of annualized IADL scale change scores revealed that 50% of MCI subjects had declined by one point, compared with 29% of NC. Conclusion: A direct IADL measure for dementia patients is able to detect small differences between MCI and NC and cross-sectionally and longitudinally, but does not distinguish between groups.

引用

页码：48 / 51

页数：4

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