Impact of FilmArray meningitis encephalitis panel on HSV testing and empiric acyclovir use in children beyond the neonatal period

被引:17
作者
Messacar, Kevin [1 ,2 ]
Gaensbauer, James T. [1 ,2 ]
Birkholz, Meghan [2 ]
Palmer, Claire [1 ]
Todd, James K. [1 ,2 ]
Tyler, Kenneth L. [1 ]
Dominguez, Samuel R. [1 ,2 ]
机构
[1] Univ Colorado, Sch Med, Aurora, CO USA
[2] Childrens Hosp Colorado, Aurora, CO USA
关键词
Meningitis; Encephalitis; Herpes; Acydovir; Pediatrics; Diagnostics; Antimicrobial stewardship; Diagnostic stewardship; HERPES-SIMPLEX-VIRUS; CEREBROSPINAL-FLUID; CRITERIA;
D O I
10.1016/j.diagmicrobio.2020.115085
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Following implementation of the FilmArray meningitis and encephalitis panel, which enables rapid syndromic cerebrospinal fluid testing, HSV testing doubled in children >60 days with suspected central nervous system infection at Children's Hospital Colorado. Acyclovir initiation was unchanged, but duration decreased. Diagnostic and antimicrobial stewardship is needed for MEP optimization. (C) 2020 Elsevier Inc. All rights reserved.
引用
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页数:3
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