Application of multifunctional nanomaterials in cancer vaccines

被引：16
作者：
Fu, Biao [1 ]
Huang, Xiaomei [1 ]
Deng, Jiaqi [2 ]
Gu, Daijiao [1 ]
Mei, Qibing [3 ]
Deng, Mingming [1 ]
Tang, Shixiao [1 ]
Lu, Muhan [1 ]
机构：
[1] Southwest Med Univ, Affiliated Hosp, Dept Gastroenterol, Zhongshan Campus 319,Sect 3,Zhongshan Rd, Luzhou 646000, Sichuan, Peoples R China
[2] Southwest Med Univ, Sch Foreign Languages, Luzhou 646000, Sichuan, Peoples R China
[3] Southwest Med Univ, Sch Pharm, Dept Pharmacol, Lab Mol Pharmacol, Luzhou 646000, Sichuan, Peoples R China
来源：
ONCOLOGY REPORTS | 2018年 / 39卷 / 03期
关键词：
multifunctional nanomaterial; cancer vaccine; cancer immunotherapy; cross-presentation; tumor microenvironment; ANTITUMOR IMMUNITY; ANTIGEN DELIVERY; DENDRITIC CELLS; MACROPHAGE POLARIZATION; CROSS-PRESENTATION; NANOPARTICLES; THERAPY; ADJUVANT; ACTIVATION; GENERATION;
D O I：
10.3892/or.2018.6206
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Tumor immunotherapy has been in development for more than a century. With the rapid developments in biotechnology research in recent years, immunotherapy has become a promising oncotherapy strategy after surgery, chemotherapy and radiotherapy. Cancer vaccines are a promising new treatment strategy and the application of nanotechnology in cancer vaccines, greatly enhances their effectiveness. Such applications indicate the bright prospects of tumor immunotherapy. The multifunctional nanomaterials used in cancer vaccines and their practical application in specific cancer vaccines are hereby reviewed. In addition, a preliminary analysis of the current and prospective use of nanotechnology with the purpose of providing solutions to cancer vaccine challenges is presented.
引用
收藏
页码：893 / 900
页数：8
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