Anemia in Critical Illness Insights into Etiology, Consequences, and Management

被引：181

作者：

Hayden, Shailaja J. ^{[1
]}

Albert, Tyler J. ^{[1
,3
]}

Watkins, Timothy R. ^{[1
,2
]}

Swenson, Erik R. ^{[1
,3
]}

机构：

[1] Univ Washington, Div Pulm & Crit Care Med, Seattle, WA 98195 USA

[2] Puget Sound Blood Ctr, Res Inst, Seattle, WA 98104 USA

[3] Vet Affairs Puget Sound Hlth Care Syst, Med Serv, Seattle, WA USA

来源：

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE | 2012年 / 185卷 / 10期

基金：

美国国家卫生研究院;

关键词：

anemia; red blood cell; transfusion; erythropoietin; critical illness; BLOOD-CELL TRANSFUSION; RANDOMIZED CONTROLLED-TRIAL; ACUTE LUNG INJURY; RESPIRATORY-DISTRESS-SYNDROME; RECOMBINANT-HUMAN-ERYTHROPOIETIN; ACUTE MYOCARDIAL-INFARCTION; SEVERE ISOVOLEMIC ANEMIA; PLACEBO-CONTROLLED TRIAL; CHRONIC KIDNEY-DISEASE; INTENSIVE-CARE UNITS;

D O I：

10.1164/rccm.201110-1915CI

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Anemia is common in the intensive care unit, and may be associated with adverse consequences. However, current options for correcting anemia are not without problems and presently lack convincing efficacy for improving survival in critically ill patients. In this article we review normal red blood cell physiology; etiologies of anemia in the intensive care unit; its association with adverse outcomes; and the risks, benefits, and efficacy of various management strategies, including blood transfusion, erythropoietin, blood substitutes, iron therapy, and minimization of diagnostic phlebotomy.

引用

页码：1049 / 1057

页数：9

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