ZEBRAFISH AS A MODEL SYSTEM TO STUDY TOXICOLOGY

被引：458

作者：

Dai, Yu-Jie ^{[1
]}

Jia, Yong-Fang ^{[2
]}

Chen, Na ^{[1
]}

Bian, Wan-Ping ^{[1
]}

Li, Qin-Kai ^{[1
]}

Ma, Yan-Bo ^{[1
]}

Chen, Yan-Ling ^{[1
]}

Pei, De-Sheng ^{[1
]}

机构：

[1] Chinese Acad Sci, Chongqing Inst Green & Intelligent Technol, Key Lab Reservoir Aquat Environm, Chongqing, Peoples R China

[2] Henan Normal Univ, Coll Life Sci, Xinxiang, Peoples R China

来源：

ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY | 2014年 / 33卷 / 01期

基金：

中国国家自然科学基金;

关键词：

Transgenic zebrafish; Environmental pollution; Monitoring; Model system; Toxicology; DANIO-RERIO; BISPHENOL-A; IN-VIVO; TRANSGENIC ZEBRAFISH; GENE-EXPRESSION; DNA-DAMAGE; PERMETHRIN ENANTIOMERS; DEVELOPMENTAL TOXICITY; OXIDATIVE STRESS; METHYL PARATHION;

D O I：

10.1002/etc.2406

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Monitoring and assessing the effects of contaminants in the aquatic eco-environment is critical in protecting human health and the environment. The zebrafish has been widely used as a prominent model organism in different fields because of its small size, low cost, diverse adaptability, short breeding cycle, high fecundity, and transparent embryos. Recent studies have demonstrated that zebrafish sensitivity can aid in monitoring environmental contaminants, especially with the application of transgenic technology in this area. The present review provides a brief overview of recent studies on wild-type and transgenic zebrafish as a model system to monitor toxic heavy metals, endocrine disruptors, and organic pollutants for toxicology. The authors address the new direction of developing high-throughput detection of genetically modified transparent zebrafish to open a new window for monitoring environmental pollutants. Environ Toxicol Chem 2014;33:11-17. (c) 2013 SETAC

引用

页码：11 / 17

页数：7

共 92 条

[61] Gonad development and vitellogenin production in zebrafish (Danio rerio) exposed to ethinylestradiol and methyltestosterone [J].

Örn, S ;

Holbech, H ;

Madsen, TH ;

Norrgren, L ;

Petersen, GI .

AQUATIC TOXICOLOGY, 2003, 65 (04) :397-411

[62] ZEBRAFISH AS DEVELOPMENTAL MODELS [J].

PAGE, LM .

SCIENCE, 1990, 250 (4986) :1320-1320

[63] FIELD EVALUATION OF BENZOPYRENE HYDROXYLASE INDUCTION AS A MONITOR FOR MARINE PETROLEUM POLLUTION [J].

PAYNE, JF .

SCIENCE, 1976, 191 (4230) :945-946

[64] Quantitative assessment of the embryotoxic potential of NSO-heterocyclic compounds using zebrafish (Danio rerio) [J].

Peddinghaus, Sabrina ;

Brinkmann, Markus ;

Bluhm, Kerstin ;

Sagner, Anne ;

Hinger, Gunnar ;

Braunbeck, Thomas ;

Eisentraeger, Adolf ;

Tiehm, Andreas ;

Hollert, Henner ;

Keiter, Steffen H. .

REPRODUCTIVE TOXICOLOGY, 2012, 33 (02) :224-232

[65] Zebrafish as a model system to study DNA damage and repair [J].

Pei, De-Sheng ;

Strauss, Phyllis R. .

MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 2013, 743 :151-159

[66] A novel regulatory circuit in base excision repair involving AP endonuclease 1, Creb1 and DNA polymerase β [J].

Pei, De-Sheng ;

Yang, Xiao-Jie ;

Liu, Wei ;

Guikema, Jeroen E. J. ;

Schrader, Carol E. ;

Strauss, Phyllis R. .

NUCLEIC ACIDS RESEARCH, 2011, 39 (08) :3156-3165

[67] Distinct Neuroblastoma-associated Alterations of PHOX2B Impair Sympathetic Neuronal Differentiation in Zebrafish Models [J].

Pei, Desheng ;

Luther, William ;

Wang, Wenchao ;

Paw, Barry H. ;

Stewart, Rodney A. ;

George, Rani E. .

PLOS GENETICS, 2013, 9 (06)

[68] A zebrafish scale assay to monitor dioxin-like activity in surface water samples [J].

Pelayo, Sergi ;

Lopez-Roldan, Ramon ;

Gonzalez, Susana ;

Casado, Marta ;

Raldua, Demetrio ;

Cortina, Jose Luis ;

Pina, Benjamin .

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2011, 401 (06) :1861-1869

[69] Developmental sub-chronic exposure to chlorpyrifos reduces anxiety-related behavior in zebrafish larvae [J].

Richendrfer, Holly ;

Pelkowski, Sean D. ;

Colwill, Ruth M. ;

Creton, Robbert .

NEUROTOXICOLOGY AND TERATOLOGY, 2012, 34 (04) :458-465

[70] Acetylcholinesterase activity and antioxidant capacity of zebrafish brain is altered by heavy metal exposure [J].

Richetti, S. K. ;

Rosemberg, D. B. ;

Ventura-Lima, J. ;

Monserrat, J. M. ;

Bogo, M. R. ;

Bonan, C. D. .

NEUROTOXICOLOGY, 2011, 32 (01) :116-122

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