Wetting-Induced Coalescence of Nanoliter Drops as Microreactors in Microfluidics

被引:27
作者
Deng, Nan-Nan [1 ]
Sun, Jian [1 ]
Wang, Wei [1 ]
Ju, Xiao-Jie [1 ]
Xie, Rui [1 ]
Chu, Liang-Yin [1 ,2 ,3 ]
机构
[1] Sichuan Univ, Sch Chem Engn, Chengdu 610065, Sichuan, Peoples R China
[2] Sichuan Univ, State Key Lab Polymer Mat Engn, Chengdu 610065, Sichuan, Peoples R China
[3] Sichuan Univ, Collaborat Innovat Ctr Biomat Sci & Technol, Chengdu 610065, Sichuan, Peoples R China
基金
中国国家自然科学基金;
关键词
drop coalescence; drop engulfing; wetting; microreactor; microfluidics; EMULSIONS; MICROPARTICLES; CHEMISTRY; DROPLETS;
D O I
10.1021/am500563z
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Controllable one-to-one coalescence of surfactant-stabilized nanoliter water drops is successfully achieved from wetting-induced drop engulfing in microfluidics by surrounding one of the drops with a thin layer of immiscible wetting fluid. This wetting layer can spread over the other drop to drain away the liquid film between the two drops, thereby inducing coalescence. This innovative approach is totally spontaneous and highly potential in a myriad of fields, such as quantitative analysis, microreaction, and high-throughput injection. To demonstrate this potential, we successfully perform the drop-coalescence-triggered microreaction in microchannels for pH indicator and syntheses of functional materials including micro- and nanoparticles.
引用
收藏
页码:3817 / 3821
页数:5
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