Electrospun collagen and its applications in regenerative medicine

被引：42

作者：

Fullana, Matthew J. ^{[1
]}

Wnek, Gary E. ^{[1
]}

机构：

[1] Case Western Reserve Univ, Dept Macromol Sci & Engn, Cleveland, OH 44106 USA

来源：

DRUG DELIVERY AND TRANSLATIONAL RESEARCH | 2012年 / 2卷 / 05期

关键词：

Electrospinning; Collagen; Regenerative medicine; Tissue engineering; Nanofiber; Scaffolds; Composite; Cross-linking; CROSS-LINKING; VASCULAR GRAFT; SCAFFOLDS; NANOFIBERS; FIBERS; ELASTIN; POLYCAPROLACTONE; MATRICES; TISSUES; ZEIN;

D O I：

10.1007/s13346-012-0087-x

中图分类号：

TH7 [仪器、仪表];

学科分类号：

0804 ; 080401 ; 081102 ;

摘要：

In recent years, electrospinning has increased in popularity as a processing technique for obtaining nanometer-to-micron diameter polymer fibers collected to form a nonwoven scaffold. It possesses the ability to process collagen into nanofibrous scaffolds which have been used for a number of applications, such as artificial vascular grafts and for wound repair. This paper offers a review of some of the basic yet essential aspects of producing nanofibrous scaffolds of collagen by electrospinning. A primer to collagen structure, cross-linking techniques, and electrospinning principles is provided, along with some of the many applications of these unique materials.

引用

页码：313 / 322

页数：10

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