A self antigen reopens the games in pancreatic cancer

被引：12

作者：

Cappello, Paola

Novelli, Francesco ^{[1
]}

机构：

[1] Univ Turin, CERMS, Turin, Italy

来源：

ONCOIMMUNOLOGY | 2013年 / 2卷 / 06期

关键词：

alpha-enolase; cancer immunotherapy; DNA vaccination; mouse models; pancreatic cancer; DUCTAL ADENOCARCINOMA;

D O I：

10.4161/onci.24384

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We have recently demonstrated that the administration of a plasmid coding for -enolase can elicit robust immune responses in genetically engineered mice that spontaneously develop pancreatic cancer, resulting in a significant improvement of their survival. This approach provides a springboard for the elaboration of new forms of immunotherapy for pancreatic cancer.

引用

页数：3

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