Transition-metal-catalyzed C-H functionalization of pyrazoles

被引：35

作者：

Kang, Eunsu ^{[1
,2
]}

Kim, Hyun Tae ^{[1
,2
]}

Joo, Jung Min ^{[1
,2
]}

机构：

[1] Pusan Natl Univ, Dept Chem, Busan 46241, South Korea

[2] Pusan Natl Univ, Chem Inst Funct Mat, Busan 46241, South Korea

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2020年 / 18卷 / 32期

关键词：

DIRECT ARYLATION; UBIQUITOUS FUNCTIONALITY; GENERAL-APPROACH; HETEROARENES; ACTIVATION; ALKENYLATION; BORYLATION; REACTIVITY; AMINATION; ALKYNES;

D O I：

10.1039/d0ob01265c

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This review describes recent advances in transition-metal-catalyzed C-H functionalization reactions of pyrazoles to form new C-C and C-heteroatom bonds on the pyrazole ring. In contrast to traditional cross-coupling reactions that require pre-functionalized pyrazoles, direct C-H functionalization reactions provide access to a wide range of functionalized pyrazoles in a single step. Various strategies are presented and the efficiency and regioselectivity are described with respect to the types of functional groups that are installed.

引用

收藏

页码：6192 / 6210

页数：19

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