Successful treatment of ventriculostomy-related meningitis caused by vancomycin-resistant Enterococcus with intravenous and intraventricular quinupristin/dalfopristin

被引:30
作者
Williamson, JC
Glazier, SS
Peacock, JE
机构
[1] Wake Forest Univ, Baptist Med Ctr, Dept Pharm, Winston Salem, NC 27157 USA
[2] Wake Forest Univ, Sch Med, Dept Internal Med, Infect Dis Sect, Winston Salem, NC 27157 USA
[3] Wake Forest Univ, Sch Med, Dept Neurosurg, Div Surg Sci, Winston Salem, NC 27157 USA
关键词
quinupristin; dalfopristin; Enterococcus; vancomycin; shunt; meningitis; linezolid; intraventricular;
D O I
10.1016/S0303-8467(01)00180-9
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We report a case of ventriculostomy-related meningitis caused by vancomycin-resistant Enterococcus faecium (VRE). The patient was successfully treated with administration of quinupristin/dalfopristin by both intravenous and intraventricular routes. A brief review of the literature is provided, which indicates that optimal management with quinupristin,dalfopristin should include daily intraventricular doses of at least 2 mg. (C) 2002 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:54 / 56
页数:3
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