The role of spread through air spaces (STAS) in lung adenocarcinoma prognosis and therapeutic decision making

被引：25
作者：
Toki, Maria, I [1 ,3 ]
Harrington, Kevin [2 ]
Syrigos, Konstantinos N. [3 ]
机构：
[1] Yale Univ, Sch Med, Dept Pathol, New Haven, CT 06510 USA
[2] Inst Canc Res Royal Marsden, London, England
[3] Natl & Kapodistrian Univ Athens, Athens, Greece
来源：
LUNG CANCER | 2020年 / 146卷
关键词：
NSCLC; Lung cancer; STAS; Adenocarcinoma; SQUAMOUS-CELL CARCINOMA; TUMOR SPREAD; AEROGENOUS SPREAD; CLINICOPATHOLOGICAL CHARACTERISTICS; MICROPAPILLARY PATTERN; LIMITED RESECTION; TISSUE FRAGMENTS; RECURRENCE; IMPACT; EXPRESSION;
D O I：
10.1016/j.lungcan.2020.04.026
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Spread through air spaces (STAS) was included as a novel pattern of invasion in lung adenocarcinoma by the World Health Organization in 2015. Since then, multiple studies have investigated the association of STAS with clinicopathological and molecular features and its implication in the prognosis of early stage lung cancer patients undergoing different surgery types. The aim of this comprehensive review is to present current data on the role of STAS and its perspective in lung adenocarcinoma management.
引用
收藏
页码：127 / 133
页数：7
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