Collagen Type I: A Versatile Biomaterial

被引：57

作者：

Chowdhury, Shiplu Roy ^{[1
]}

Busra, Mohd Fauzi Mh ^{[1
]}

Lokanathan, Yogeswaran ^{[1
]}

Ng, Min Hwei ^{[1
]}

Law, Jia Xian ^{[1
]}

Cletus, Ude Chinedu ^{[2
]}

Idrus, Ruszymah Binti Haji ^{[3
]}

机构：

[1] Univ Kebangsaan Malaysia, Tissue Engn Ctr, Fac Med, Kuala Lumpur, Malaysia

[2] Natl Def Univ Malaysia, Bioartificial Organ & Regenerat Med Unit, Kuala Lumpur, Malaysia

[3] Univ Kebangsaan Malaysia, Dept Physiol, Fac Med, Kuala Lumpur, Malaysia

来源：

NOVEL BIOMATERIALS FOR REGENERATIVE MEDICINE | 2018年 / 1077卷

关键词：

Collagen type I; Biomaterial; Fabrication; Tissue engineering; Tissue substitutes; In vitro model; Drug delivery system; TISSUE-ENGINEERED SKIN; AUTOLOGOUS CHONDROCYTE IMPLANTATION; ENDOTHELIAL GROWTH-FACTOR; DERMAL REGENERATION TEMPLATE; PARTIAL-THICKNESS BURNS; MESENCHYMAL STEM-CELLS; BOVINE CAROTID-ARTERY; CLINICAL-TRIAL; CROSS-LINKING; EXPANDED POLYTETRAFLUOROETHYLENE;

D O I：

10.1007/978-981-13-0947-2_21

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

Collagen type I is the most abundant matrix protein in the human body and is highly demanded in tissue engineering, regenerative medicine, and pharmaceutical applications. To meet the uprising demand in biomedical applications, collagen type I has been isolated from mammalians (bovine, porcine, goat and rat) and non-mammalians (fish, amphibian, and sea plant) source using various extraction techniques. Recent advancement enables fabrication of collagen scaffolds in multiple forms such as film, sponge, and hydrogel, with or without other biomaterials. The scaffolds are extensively used to develop tissue substi-tutes in regenerating or repairing diseased or damaged tissues. The 3D scaffolds are also used to develop in vitro model and as a vehicle for delivering drugs or active compounds.

引用

页码：389 / 414

页数：26

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