A highly selective and sensitive colorimetric and near-infrared fluorescent turn-on probe for rapid detection of palladium in drugs and living cells

被引：57

作者：

Xia, Qingfeng ^{[1
]}

Feng, Shumin ^{[1
]}

Liu, Dandan ^{[1
]}

Feng, Guoqiang ^{[1
]}

机构：

[1] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, 152 Luoyu Rd, Wuhan 430079, Hubei, Peoples R China

来源：

SENSORS AND ACTUATORS B-CHEMICAL | 2018年 / 258卷

基金：

中国国家自然科学基金;

关键词：

Palladium; Colorimetric; NIR fluorescent probe; Drug; Living cell; PD(0) MEDIATED REACTION; PD-CATALYZED REACTIONS; FAR-RED; DUAL PROBE; PLATINUM; FLUOROPHORE; RHODIUM; DISCRIMINATION; SPECTROMETRY; SENSOR;

D O I：

10.1016/j.snb.2017.11.099

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Palladium contamination has attracted widespread attention due to the toxicity and the wide use of palladium species. Consequently, development of convenient and effective methods for palladium detection is of great importance. Herein, a new colorimetric and near-infrared (NIR) fluorescent turn-on probe based on the Tsuji-Trost reaction for palladium was developed. This probe can be used to detect palladium in aqueous solution (for example, in pH 7.4 PBS buffer with 0-20% DMSO) under mild conditions with high selectivity and sensitivity, giving rapid (within 2 min) and distinct dual colorimetric and NIR fluorescent turn-on signal changes with a detection limit as low as 2.2 nM. A paper test strip system was prepared with this probe for a convenient visual detection of palladium. In addition, MTT assays showed that this probe has low cytotoxicity and detection of palladium in real drug samples and living cells was successfully applied with this probe, indicating this probe has a good application prospect. (c) 2017 Elsevier B.V. All rights reserved.

引用

页码：98 / 104

页数：7

共 49 条

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