Transmitted drug resistance in French HIV-2-infected patients

被引：12
作者：
Charpentier, Charlotte [1 ]
Visseaux, Benoit [1 ]
Benard, Antoine [2 ]
Peytavin, Gilles [3 ]
Damond, Florence [1 ]
Roy, Celine [2 ]
Taieb, Audrey [2 ]
Chene, Genevieve [2 ]
Matheron, Sophie [4 ]
Brun-Vezinet, Francoise [1 ]
Descamps, Diane [1 ]
机构：
[1] Univ Paris 07, Grp Hosp Bichat Claude Bernard, AP HP, HUPNVS,PRES Sorbonne Paris Cite,Lab Virol, Paris, France
[2] Bordeaux Segalen Univ, ISPED, INSERM, U897, Bordeaux, France
[3] Univ Paris 07, Grp Hosp Bichat Claude Bernard, AP HP, HUPNVS,PRES Sorbonne Paris Cite,Lab Pharmacol, Paris, France
[4] Univ Paris 07, Grp Hosp Bichat Claude Bernard, AP HP,HUPNVS,PRES Sorbonne Paris Cite, Serv Malad Infect & Trop, Paris, France
来源：
AIDS | 2013年 / 27卷 / 10期
关键词：
IMMUNODEFICIENCY-VIRUS TYPE-2; HIV-2; INFECTED-PATIENTS; ANTIRETROVIRAL THERAPY; PROTEASE INHIBITORS; MUTATIONS; SURVEILLANCE; PREVALENCE; SUSCEPTIBILITY; MULTICENTER; SELECTION;
D O I：
10.1097/QAD.0b013e32836207f3
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
We report the first transmitted drug resistance survey study in HIV-2-infected patients living in France. The prevalence of transmitted drug resistance was 5.0% (95% confidence interval, 0.1-9.9) with mutations detected only in protease, not in reverse transcriptase. In this series, 10% of patients displayed X4/dual-mixed viruses. These findings classified the rate of transmitted drug resistance in the HIV-2 French Cohort as low prevalence.
引用
收藏
页码：1671 / 1674
页数：4
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