Crystallization of a globular protein in lipid cubic phase

被引：18
作者：
Tanaka, S [1 ]
Egelhaaf, SU [1 ]
Poon, WCK [1 ]
机构：
[1] Univ Edinburgh, Sch Phys, JCMB, Edinburgh EH9 3JZ, Midlothian, Scotland
来源：
PHYSICAL REVIEW LETTERS | 2004年 / 92卷 / 12期
基金：
英国工程与自然科学研究理事会;
关键词：
D O I：
10.1103/PhysRevLett.92.128102
中图分类号：
O4 [物理学];
学科分类号：
0702 ;
摘要：
We studied the crystallization of a globular protein, lysozyme, in the cubic phase of the lipid mono-olein. The solubility of lysozyme in salt solution decreased by a factor of similar to4 when confined in cubic phase. Monte Carlo simulations and calculations show that this can be explained by the confinement of lysozyme molecules to the narrow water cells in the cubic phase.
引用
收藏
页码：128102 / 1
页数：4
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