A microwave assisted intramolecular-furan-Diels-Alder approach to 4-substituted indoles

被引：37

作者：

Petronijevic, Filip ^{[1
]}

Timmons, Cody ^{[1
]}

Cuzzupe, Anthony ^{[1
]}

Wipf, Peter ^{[1
]}

机构：

[1] Univ Pittsburgh, Dept Chem, Pittsburgh, PA 15260 USA

来源：

CHEMICAL COMMUNICATIONS | 2009年 / 01期

关键词：

ALKALOIDS; CYCLOADDITION; INDOLINES; CHEMISTRY;

D O I：

10.1039/b816989f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The key steps of a versatile new protocol for the convergent synthesis of 3,4-disubstituted indoles are the addition of an alpha-lithiated alkylaminofuran to a carbonyl compound, a microwave-accelerated intramolecular Diels-Alder cyclo-addition and an in situ double aromatization reaction.

引用

页码：104 / 106

页数：3

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