COMMUNITY ASSOCIATED METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS

被引:2
作者
Mertens, R. [1 ]
Seyler, L. [1 ]
Lacor, P. [1 ]
Denis, O. [2 ]
机构
[1] UZ Brussel, Infect Dis Unit, Dept Internal Med, Brussels, Belgium
[2] Univ Libre Bruxelles, Hop Erasme, Dept Microbiol, Lab Reference MRSA Staphylocoques, Brussels, Belgium
关键词
Staphylococcus aureus; methicillin-resistant Staphylococcus aureu; CA-MRSA; Panton-Valentine leukocidin; PVL; SOFT-TISSUE INFECTIONS; ACQUIRED PNEUMONIA; NECROTIZING FASCIITIS; SKIN; EPIDEMIOLOGY; GUIDELINES; ANTIBIOTICS; VANCOMYCIN; MANAGEMENT; EMERGENCE;
D O I
10.2143/ACB.67.4.2062665
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Community associated methicillin resistant Staphylococcus aureus (CA-MRSA) is an emergent infectious pathogen that might become an important public-health problem. Indeed, unique strains of S. aureus that combine specific virulence factors with resistance against frequently used antibiotics have been associated with severe community acquired infections in otherwise healthy and often younger people. This is especially the case in the USA, were these strains now represent a major part of staphylococcal infections in the outpatient setting. But, severe infections with CA-MRSA strains have already been reported in Belgium as well. This article summarizes the current knowledge on CA-MRSA as an emergent pathogen and discusses its clinical management.
引用
收藏
页码:235 / 240
页数:6
相关论文
共 50 条
[31]  
LOEB M, 2003, COCHRANE DB SYST REV, V4, DOI DOI 10.1002/14651858.CD003340
[32]   Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults [J].
Mandell, Lionel A. ;
Wunderink, Richard G. ;
Anzueto, Antonio ;
Bartlett, John G. ;
Campbell, G. Douglas ;
Dean, Nathan C. ;
Dowell, Scott F. ;
File, Thomas M., Jr. ;
Musher, Daniel M. ;
Niederman, Michael S. ;
Torres, Antonio ;
Whitney, Cynthia G. .
CLINICAL INFECTIOUS DISEASES, 2007, 44 :S27-S72
[33]   Community-associated methicillin-resistant Staphylococcus aureus isolates causing healthcare-associated infections [J].
Maree, Cynthia L. ;
Daum, Robert S. ;
Boyle-Vavra, Susan ;
Matayoshi, Kelli ;
Miller, Loren G. .
EMERGING INFECTIOUS DISEASES, 2007, 13 (02) :236-242
[34]   Necrotizing fasciitis caused by community-associated methicillin-resistant Staphylococcus aureus in Los Angeles [J].
Miller, LG ;
Perdreau-Remington, F ;
Rieg, G ;
Mehdi, S ;
Perlroth, J ;
Bayer, AS ;
Tang, AW ;
Phung, TO ;
Spellberg, B .
NEW ENGLAND JOURNAL OF MEDICINE, 2005, 352 (14) :1445-1453
[35]   A prospective investigation of outcomes after hospital discharge for endemic, community-acquired methicillin-resistant and -susceptible Staphylococcus aureus skin infection [J].
Miller, Loren G. ;
Quan, Clifford ;
Shay, Anthony ;
Mostafaie, Katayoun ;
Bharadwa, Kiran ;
Tan, Nelly ;
Matayoshi, Kelli ;
Cronin, Jason ;
Tan, Jennifer ;
Tagudar, Grace ;
Bayer, Arnold S. .
CLINICAL INFECTIOUS DISEASES, 2007, 44 (04) :483-492
[36]   Clinical and epidemiologic characteristics cannot distinguish community-associated methicillin-resistant Staphylococcus aureus infection from methicillin-susceptible S-aureus infection:: A prospective investigation [J].
Miller, Loren G. ;
Perdreau-Remington, Franciose ;
Bayer, Arnold S. ;
Diep, Binh ;
Tan, Nelly ;
Bharadwa, Kiran ;
Tsui, Jennifer ;
Perlroth, Joshua ;
Shay, Anthony ;
Tagudar, Grace ;
Ibebuogu, Uzoma ;
Spellberg, Brad .
CLINICAL INFECTIOUS DISEASES, 2007, 44 (04) :471-482
[37]   Staphylococcus aureus: A Community Pathogen [J].
Miller, Loren G. ;
Kaplan, Sheldon L. .
INFECTIOUS DISEASE CLINICS OF NORTH AMERICA, 2009, 23 (01) :35-+
[38]   Methicillin-resistant S-aureus infections among patients in the emergency department [J].
Moran, Gregory J. ;
Krishnadasan, Anusha ;
Gorwitz, Rachel J. ;
Fosheim, Gregory E. ;
McDougal, Linda K. ;
Carey, Roberta B. ;
Talan, David A. .
NEW ENGLAND JOURNAL OF MEDICINE, 2006, 355 (07) :666-674
[39]   Central nervous system invasion by community-acquired meticillin-resistant Staphylococcus aureus [J].
Naesens, Reinout ;
Ronsyn, Mark ;
Druwe, Patrick ;
Denis, Olivier ;
Ieven, Margareta ;
Jeurissen, Axel .
JOURNAL OF MEDICAL MICROBIOLOGY, 2009, 58 (09) :1247-1251
[40]   Comparison of community- and health care-associated methicillin-resistant Staphylococcus aureus infection [J].
Naimi, TS ;
LeDell, KH ;
Como-Sabetti, K ;
Borchardt, SM ;
Boxrud, DJ ;
Etienne, J ;
Johnson, SK ;
Vandenesch, F ;
Fridkin, S ;
O'Boyle, C ;
Danila, RN ;
Lynfield, R .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2003, 290 (22) :2976-2984