Oncogenic proteins as tumor antigens

被引：113
作者：
Disis, ML
Cheever, MA
机构：
[1] University of Washington, Division of Oncology, Box 36527, Seattle
来源：
CURRENT OPINION IN IMMUNOLOGY | 1996年 / 8卷 / 05期
关键词：
D O I：
10.1016/S0952-7915(96)80079-3
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Human immune responses to oncogenic proteins have been reported and are continuing to be defined. Immunity to nonmutated overexpressed oncoproteins as well as to mutated or unique cancer-specific oncoproteins has been identified. Immune system based treatments targeting oncogenic proteins have shown therapeutic efficacy in animals models and are currently being translated into human clinical trials.
引用
收藏
页码：637 / 642
页数：6
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