Cobalt-catalysed synthesis of highly substituted styrene derivatives via arylzincation of alkynes

被引：37

作者：

Corpet, Martin ^{[1
]}

Gosmini, Corinne ^{[1
]}

机构：

[1] Ecole Polytech, CNRS, Lab Heteroelements & Coordinat, F-91128 Palaiseau, France

来源：

CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 94期

关键词：

TETRASUBSTITUTED ALKENES; FUNCTIONALIZED ARYLZINC; AROMATIC HALIDES; ZINC DUST; CARBOZINCATION; EFFICIENT; VINYLATION;

D O I：

10.1039/c2cc36676b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new two-step procedure was developed by carbozincation of internal and terminal alkynes to synthesise highly functionalised vinylzinc bromides. Various tri and tetrasubstituted alkenes were prepared in moderate to good yields under mild reaction conditions in a stereo-selective manner. This methodology represents an interesting alternative to previously known methods.

引用

页码：11561 / 11563

页数：3

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