Screening of ligands for the Ullmann synthesis of electron-rich diaryl ethers

被引：25

作者：

Otto, Nicola ^{[1
]}

Opatz, Till ^{[1
]}

机构：

[1] Johannes Gutenberg Univ Mainz, Inst Organ Chem, D-55128 Mainz, Germany

来源：

BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY | 2012年 / 8卷

关键词：

catalysis; C-O bond formation; diaryl ethers; nucleophilic aromatic substitution; Ullmann-type coupling; C-O BOND; ARYL HALIDES; COPPER; ACID; VANCOMYCIN; ARYLATION; CATALYSTS; PROGRESS; PHENOLS;

D O I：

10.3762/bjoc.8.122

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In the search for new ligands for the Ullmann diaryl ether synthesis, permitting the coupling of electron-rich aryl bromides at relatively low temperatures, 56 structurally diverse multidentate ligands were screened in a model system that uses copper iodide in acetonitrile with potassium phosphate as the base. The ligands differed largely in their performance, but no privileged structural class could be identified.

引用

页码：1105 / 1111

页数：7

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