Mixed Epithelial and Stromal Tumor of the Kidney with Sarcomatous Transformation Metastatic to the Lung A Case Report

被引：0

作者：

Ozluk, Yasemin ^{[1
]}

Sari, Sule Ozturk ^{[1
]}

Guzel, Nalan Turan ^{[1
]}

Firat, Pinar ^{[1
]}

Akbulut, Fatih ^{[2
]}

Kilicaslan, Isin ^{[1
]}

机构：

[1] Istanbul Univ, Dept Pathol, Istanbul Fac Med, TR-34390 Istanbul, Turkey

[2] Haseki Training & Res Hosp, Dept Urol, Istanbul, Turkey

来源：

ANALYTICAL AND QUANTITATIVE CYTOPATHOLOGY AND HISTOPATHOLOGY | 2015年 / 37卷 / 03期

关键词：

biphasic tumor; immunohistochemistry; kidney; kidney neoplasm; metastasis; mixed epithelial and stromal tumor; sarcoma; sarcomatous transformation; ADULT MESOBLASTIC NEPHROMA; CLEAR-CELL SARCOMA; CYSTIC NEPHROMA; RENAL TUMORS; DIFFERENTIATION; SPECTRUM; FEATURES; ENTITY;

D O I：

暂无

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

BACKGROUND: Malignant transformation of mixed epithelial and stromal tumor (MEST) of the kidney is a very rare entity. We report an unusual case with a review of the literature. CASE: A 25-year-old woman underwent surgery for an 8-cm biphasic renal tumor, which was diagnosed as MEST of the kidney. High cellularity, mitoses, and nuclear atypia seen in the stromal component were compatible with a sarcomatous transformation in MEST. The patient also had pulmonary metastatic nodules that were resected 2 months after the nephrectomy. Metastatic pulmonary tumors were morphologically identical to the sarcomatous component of the renal tumor and showed pulmonary epithelial hyperplasia with a phyllodes-like pattern. CONCLUSION: Although MEST of the kidney is known as a benign tumor, malignant transformation, mostly sarcomatous type, should be considered in the diagnosis.

引用

页码：199 / 205

页数：7

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