A novel approach to normal responder patient with repeated implantation failures - a case report

被引：21

作者：

Orvieto, Raoul ^{[1
,2
]}

Brengauz, Masha ^{[1
,2
]}

Feldman, Baruch ^{[1
,2
]}

机构：

[1] Chaim Sheba Med Ctr Tel Hashomer, Dept Obstet & Gynecol, Infertil & IVF Unit, Ramat Gan, Israel

[2] Tel Aviv Univ, Sackler Fac Med, IL-69978 Tel Aviv, Israel

来源：

GYNECOLOGICAL ENDOCRINOLOGY | 2015年 / 31卷 / 06期

关键词：

Frozen-thawed embryo transfer; IVF outcome; local injury; mid-luteal GnRH-agonist; repeated implantation failures; ultrashort flare GnRH-agonist/GnRH antagonist; GNRH-AGONIST; OVARIAN STIMULATION; RECEPTIVITY;

D O I：

10.3109/09513590.2015.1005595

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We describe a case of normal responder patients with repeated implantation failure who was offered the combination of the ultrashort GnRH-ag/ GnRH-ant COH protocol, followed by endometrial injury and a subsequent natural cycle frozen-thawed embryos transfer. The patient conceived following the natural FET cycle that was supported by luteal daily progesterone, with the additional single injection of HCG and GnRH-agonist, on day of ET and 4 days later, respectively. This combined approach seems to be a valuable tool in the armamentarium for treating normal responder patients with repeated implantation failures and should be further examined in large randomized controlled trials.

引用

页码：435 / 437

页数：3

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