Asymmetric Epoxidation of Conjugated Olefins with Dioxygen

被引：50

作者：

Koya, Shota ^{[1
,2
]}

Nishioka, Yota ^{[1
,2
]}

Mizoguchi, Hirotaka ^{[1
,2
]}

Uchida, Tatsuya ^{[1
,2
]}

Katsuki, Tsutomu ^{[1
,2
]}

机构：

[1] Kyushu Univ, Grad Sch, Fac Sci, Dept Chem,Higashi Ku, Fukuoka 8128581, Japan

[2] Kyushu Univ, Int Inst Carbon Neutral Energy Res WPI I2CNER, Higashi Ku, Fukuoka 8128581, Japan

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2012年 / 51卷 / 33期

关键词：

aerobic oxidation; asymmetric catalysis; dioxygen; epoxidation; ruthenium; WATER-SOLUBLE METALLOPORPHYRINS; AEROBIC OXIDATION; KINETIC RESOLUTION; MOLECULAR-OXYGEN; COMPLEXES; PRECURSORS; IRON; DIHYDROXYLATION; AZIRIDINATION; TAUTOMERISM;

D O I：

10.1002/anie.201201848

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A complex situation: Asymmetric epoxidation of conjugated olefins was achieved at room temperature using ruthenium complex 1 as the catalyst and air as the oxidant to give epoxides in up to 95 % ee (see scheme). When the product was acid sensitive, the reaction was carried out at 0 °C under oxygen. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：8243 / 8246

页数：4

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