First detection of Borrelia miyamotoi in Ixodes ricinus ticks from northern Italy

被引:19
作者
Ravagnan, Silvia [1 ]
Tomassone, Laura [2 ]
Montarsi, Fabrizio [1 ]
Krawczyk, Aleksandra Iwona [3 ]
Mastrorilli, Eleonora [1 ]
Sprong, Hein [3 ]
Milani, Adelaide [1 ]
Rossi, Luca [2 ]
Capelli, Gioia [1 ]
机构
[1] Ist Zooprofilatt Sperimentale Venezie, Legnaro, Italy
[2] Univ Turin, Dipartimento Sci Vet, Grugliasco, Italy
[3] Natl Inst Publ Hlth & Environm RIVM, Bilthoven, Netherlands
来源
PARASITES & VECTORS | 2018年 / 11卷
关键词
Borrelia miyamotoi; Ixodes ricinus; Zoonosis; Northern Italy; RELAPSING FEVER SPIROCHETE; BURGDORFERI SENSU-LATO; LYME-DISEASE; HUMANS; EUROPE;
D O I
10.1186/s13071-018-2713-z
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
Background: Borrelia miyamotoi is a spirochete transmitted by several ixodid tick species. It causes a relapsing fever in humans and is currently considered as an emerging pathogen. In Europe, B. miyamotoi seems to occur at low prevalence in Ixodes ricinus ticks but has a wide distribution. Here we report the first detection of B. miyamotoi in Ixodes ricinus ticks collected in two independent studies conducted in 2016 in the north-eastern and north-western Alps, Italy. Results: Three out of 405 nymphs (0.74%) tested positive for Borrelia miyamotoi. In particular, B. miyamotoi was found in 2/365 nymphs in the western and in 1/40 nymphs in the eastern alpine area. These are the first findings of B. miyamotoi in Italy. Conclusions: Exposure to B. miyamotoi and risk of human infection may occur through tick bites in northern Italy. Relapsing fever caused by Borrelia miyamotoi has not yet been reported in Italy, but misdiagnoses with tick-borne encephalitis, human granulocytic anaplasmosis or other relapsing fever can occur. Our findings suggest that B. miyamotoi should be considered in the differential diagnosis of febrile patients originating from Lyme borreliosis endemic regions. The distribution of this pathogen and its relevance to public health need further investigation.
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相关论文
共 31 条
  • [1] Barakova I, 2017, TICKS TICK BORNE DIS
  • [2] Borrelia miyamotoi-Associated Neuroborreliosis in Immunocompromised Person
    Boden, Katharina
    Lobenstein, Sabine
    Hermann, Beate
    Margos, Gabriele
    Fingerle, Volker
    [J]. EMERGING INFECTIOUS DISEASES, 2016, 22 (09) : 1617 - 1620
  • [3] Are Apodemus spp. mice and Myodes glareolus reservoirs for Borrelia miyamotoi, Candidatus Neoehrlichia mikurensis, Rickettsia helvetica, R. monacensis and Anaplasma phagocytophilum?
    Burri, C.
    Schumann, O.
    Schumann, C.
    Gemn, L.
    [J]. TICKS AND TICK-BORNE DISEASES, 2014, 5 (03) : 245 - 251
  • [4] Occurrence and identification of risk areas of Ixodes ricinus-borne pathogens: a cost-effectiveness analysis in north-eastern Italy
    Capelli, Gioia
    Ravagnan, Silvia
    Montarsi, Fabrizio
    Ciocchetta, Silvia
    Cazzin, Stefania
    Porcellato, Elena
    Babiker, Amira Mustafa
    Cassini, Rudi
    Salviato, Annalisa
    Cattoli, Giovanni
    Otranto, Domenico
    [J]. PARASITES & VECTORS, 2012, 5
  • [5] Prevalence and genetic variability of tick-borne encephalitis virus in host-seeking Ixodes ricinus in northern Italy
    Carpi, Giovanna
    Bertolotti, Luigi
    Rosati, Sergio
    Rizzoli, Annapaola
    [J]. JOURNAL OF GENERAL VIROLOGY, 2009, 90 : 2877 - 2883
  • [6] Detection of Babesia EU1 in Ixodes ricinus ticks in northern Italy
    Cassini, Rudi
    Bonoli, Cristina
    Montarsi, Fabrizio
    Tessarin, Cinzia
    Marcer, Federica
    Galuppi, Roberta
    [J]. VETERINARY PARASITOLOGY, 2010, 171 (1-2) : 151 - 154
  • [7] Ciceroni L, 1998, MICROBIOLOGICA, V21, P407
  • [8] Genetic characterization of the human relapsing fever spirochete Borrelia miyamotoi in vectors and animal reservoirs of Lyme disease spirochetes in France
    Cosson, Jean-Francois
    Michelet, Lorraine
    Chotte, Julien
    Le Naour, Evelyne
    Cote, Martine
    Devillers, Elodie
    Poulle, Marie-Lazarine
    Huet, Dominique
    Galan, Maxime
    Geller, Julia
    Moutailler, Sara
    Vayssier-Taussat, Muriel
    [J]. PARASITES & VECTORS, 2014, 7
  • [9] GENETIC AND PHENOTYPIC ANALYSIS OF BORRELIA-MIYAMOTOI SP-NOV, ISOLATED FROM THE IXODID TICK IXODES-PERSULCATUS, THE VECTOR FOR LYME-DISEASE IN JAPAN
    FUKUNAGA, M
    TAKAHASHI, Y
    TSURUTA, Y
    MATSUSHITA, O
    RALPH, D
    MCCLELLAND, M
    NAKAO, M
    [J]. INTERNATIONAL JOURNAL OF SYSTEMATIC BACTERIOLOGY, 1995, 45 (04): : 804 - 810
  • [10] A case of meningoencephalitis by the relapsing fever spirochaete Borrelia miyamotoi in Europe
    Hovius, Joppe W. R.
    de Wever, Bob
    Sohne, Maaike
    Brouwer, Matthijs C.
    Coumou, Jeroen
    Wagemakers, Alex
    Oei, Anneke
    Knol, Henrike
    Narasimhan, Sukanya
    Hodiamont, Caspar J.
    Jahfari, Setareh
    Pals, Steven T.
    Horlings, Hugo M.
    Fikrig, Erol
    Sprong, Hein
    van Oers, Marinus H. J.
    [J]. LANCET, 2013, 382 (9892) : 658 - 658