Emerging Opportunities in the Biomedical Applications of Dendrimers

被引：23
作者：
Abd-El-Aziz, Alaa S. [1 ]
Agatemor, Christian [2 ]
机构：
[1] Univ Prince Edward Isl, Dept Chem, 550 Univ Ave, Charlottetown, PE C1A 4P3, Canada
[2] Harvard Univ, Sch Engn & Appl Sci, Cambridge, MA 02138 USA
来源：
JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS | 2018年 / 28卷 / 02期
基金：
加拿大自然科学与工程研究理事会;
关键词：
Dendrimers; Drug delivery; Biosensing; Bioimaging; Antimicrobial agents; Gene transfection; DRUG-DELIVERY; BROAD-SPECTRUM; DENDRITIC MACROMOLECULES; UNIMOLECULAR MICELLES; PHOSPHORUS DENDRIMERS; PHOTODYNAMIC THERAPY; PAMAM DENDRIMERS; POLY(AMIDOAMINE) DENDRIMER; ORGANOIRON MACROMOLECULES; HYPERBRANCHED POLYMERS;
D O I：
10.1007/s10904-017-0768-5
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
The medical field remains challenged with many unmet needs, prompting rigorous research for solutions. Dendrimers are emerging as innovative solutions to many unmet clinical needs. Indeed, commercial dendrimer-enabled gene transfection technologies exist and work is ongoing to translate many other dendrimer products into the market to assist patients. Here, we review the ongoing work on dendrimer-enabled drug delivery technologies, diagnostic platforms, and antimicrobial agents. Our goal is to inspire the continuous exploration of the dendritic scaffold to address many issues in the biomedical landscape.
引用
收藏
页码：369 / 382
页数：14
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