Safety and Efficacy of a Same-Day Low-Volume 1 L PEG Bowel Preparation in Colonoscopy for the Elderly People and People with Renal Dysfunction

被引：40

作者：

Yoshida, Naohisa ^{[1
]}

Naito, Yuji ^{[1
]}

Murakami, Takaaki ^{[1
]}

Hirose, Ryohei ^{[1
]}

Ogiso, Kiyoshi ^{[1
]}

Inada, Yutaka ^{[1
]}

Dohi, Osamu ^{[1
]}

Okayama, Tetsuya ^{[1
]}

Kamada, Kazuhiro ^{[1
]}

Uchiyama, Kazuhiko ^{[1
]}

Ishikawa, Takeshi ^{[1
]}

Handa, Osamu ^{[1
]}

Konishi, Hideyuki ^{[1
]}

Siah, Kewin Tien Ho ^{[2
]}

Yagi, Nobuaki ^{[3
]}

Itoh, Yoshito ^{[1
]}

机构：

[1] Kyoto Prefectural Univ Med, Grad Sch Med Sci, Dept Mol Gastroenterol & Hepatol, Kamigyo Ku, 465 Kajii Cho,Kawaramachi Hirokoji, Kyoto 6028566, Japan

[2] Natl Univ Singapore Hosp, Univ Med Cluster, Div Gastroenterol & Hepatol, Singapore, Singapore

[3] Murakami Mem Hosp, Dept Gastroenterol, Gifu, Japan

来源：

DIGESTIVE DISEASES AND SCIENCES | 2016年 / 61卷 / 11期

关键词：

Bowel preparation; Colonoscopy; Low-volume PEG; Ascorbic acid; The elderly; RENAL dysfunction; ENDOSCOPIC SUBMUCOSAL DISSECTION; PLUS ASCORBIC-ACID; POLYETHYLENE-GLYCOL; COLORECTAL TUMORS; RANDOMIZED-TRIAL; CLEANSING PRIOR; POLYPECTOMY; NEOPLASIA; RESECTION; POLYPS;

D O I：

10.1007/s10620-016-4262-7

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

A same-day low-volume 1 L polyethylene glycol (PEG) for bowel preparation before colonoscopy was developed to improve patients' compliance. We aimed to evaluate the efficacy and safety of this regimen especially for the elderly and patients with renal dysfunction. All consecutive patients who underwent colonoscopy in our center from November 2014 to September 2015 were included. Patients undertook a low-residue diet with 10 mL sodium picosulfate 1 day before colonoscopy. Subsequently, they had 1 L low-volume PEG (MoviPrep) and 0.5 L water 4 h before the examination. Clinical outcomes, including cleansing level using the Boston bowel preparation score (BBPS), in the elderly and special-elderly (65-79 and aeyen80 years old) were analyzed and compared with the non-elderly (18-64 years old). Additionally, patients with renal dysfunction were analyzed with respect to both complications and changes in blood parameters. A total of 5427 patients (mean age: 64.5 +/- A 13.8) were analyzed. The rate of BBPS aeyen 6 in the elderly (2761 patients), special-elderly (565 patients), and non-elderly (2101 patients) was 94.1, 91.8, and 94.6 %, respectively. In the special-elderly, the rate of renal dysfunction was 14.8 %, and no severe complications were detected after colonoscopy. Additionally, there were no severe complications in 86 patients with renal dysfunction, though elevation of hematocrit was shown after intake of 1 L PEG (before, 36.7 +/- A 6.1 vs. after, 39.0 +/- A 5.7, P = 0.006). Our study shows the safety and efficacy of same-day low-volume 1 L PEG bowel preparation in colonoscopy for the elderly and patients with renal dysfunction.

引用

页码：3229 / 3235

页数：7

共 29 条

[1] Impact of Obesity on Bowel Preparation for Colonoscopy [J].