Pluripotent genes in avian stem cells

被引：16

作者：

Jean, Christian ^{[1
,2
,3
]}

Aubel, Pauline ^{[1
,2
,3
]}

Soleihavoup, Clement ^{[1
,2
,3
]}

Bouhallier, Frantz ^{[1
,2
,3
]}

Voisin, Sophie ^{[1
,2
,3
]}

Lavial, Fabrice ^{[4
]}

Pain, Bertrand ^{[1
,2
,3
]}

机构：

[1] INSERM, Stem Cell & Brain Res Inst, U846, F-69500 Bron, France

[2] Univ Lyon 1, UMR S 846, F-69365 Lyon, France

[3] INRA, AGROBIOSTEM, USC1361, Bron, France

[4] Univ Lyon, Ctr Leon Berard, CNRS, Ctr Cancerol Lyon,INSERM,U1052,UMR5286, Lyon, France

来源：

DEVELOPMENT GROWTH & DIFFERENTIATION | 2013年 / 55卷 / 01期

关键词：

chick; embryonic stem cells; ENS1; KLF; NANOG; OCT4; pluripotency; SOX2; GROUND-STATE PLURIPOTENCY; SELF-RENEWAL; TRANSCRIPTION FACTORS; MOUSE EMBRYOS; MAINTAINS PLURIPOTENCY; CHICKEN GENOME; NANOG; OCT4; EXPRESSION; EPIBLAST;

D O I：

10.1111/dgd.12021

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Embryonic stem (ES) cells were first isolated in 1981 in the mouse from the in vitro proliferation of the inner cell mass of a 3.5 days post-coitum (dpc) blastocyst. Later on, epiblast stem cells (EpiSC) were identified from in vitro culture of the epiblast of a 6.5 dpc mouse embryo, leading to the concept of naive and primed stem cells. Among non-mammalian species, ES cells have been characterized both in birds and fish; here, we focus on cells derived from chicken and the pluripotent associated markers such as OCT4, SOX2, NANOG, and KLF, previously identified in mammalian cells. In this review, we present both published and original data regarding the involvement of those pluripotent associated genes in the ES cells and early embryo of chicken.

引用

页码：41 / 51

页数：11

共 105 条

[1] Identification of a new gene family specifically expressed in chicken embryonic stem cells and early embryo [J].