Treatment With Convalescent Plasma for Critically Ill Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Infection

被引:263
作者
Zhang, Bin [1 ]
Liu, Shuyi [1 ]
Tan, Tan [2 ]
Huang, Wenhui [1 ]
Dong, Yuhao [3 ]
Chen, Luyan [1 ]
Chen, Qiuying [1 ]
Zhang, Lu [1 ]
Zhong, Qingyang [4 ]
Zhang, Xiaoping [5 ]
Zou, Yujian [6 ]
Zhang, Shuixing [1 ]
机构
[1] Jinan Univ, Affiliated Hosp 1, Guangzhou, Guangdong, Peoples R China
[2] Xiangtan Cent Hosp, Xiangtan, Hunan, Peoples R China
[3] Guangdong Prov Peoples Hosp, Guangdong Acad Med Sci, Guangzhou, Guangdong, Peoples R China
[4] Dongguan Ninth Peoples Hosp, Dongguan, Guangdong, Peoples R China
[5] Second Peoples Hosp Zhongshan, Zhongshan, Guangdong, Peoples R China
[6] Dongguan Peoples Hosp, Dongguan, Guangdong, Peoples R China
关键词
convalescent plasma; critical illness; SARS-CoV-2; THERAPY;
D O I
10.1016/j.chest.2020.03.039
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
As of March 24, 2020, novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been responsible for 379,661 infection cases with 16,428 deaths globally, and the number is still increasing rapidly. Herein, we present four critically ill patients with SARS-CoV-2 infection who received supportive care and convalescent plasma. Although all four patients (including a pregnant woman) recovered from SARS-CoV-2 infection eventually, randomized trials are needed to eliminate the effect of other treatments and investigate the safety and efficacy of convalescent plasma therapy.
引用
收藏
页码:E9 / E13
页数:5
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