New immunosuppressive agents in pediatric transplantation

被引：13

作者：

Christina Nguyen ^{[1
]}

Shapiro, Ron ^{[2
]}

机构：

[1] UPMC, Childrens Hosp Pittsburgh, Div Pediat Nephrol, Pittsburgh, PA 15219 USA

[2] UPMC, Thomas E Starzl Transplantat Inst, Div Transplant Surg, Pittsburgh, PA USA

来源：

CLINICS | 2014年 / 69卷

关键词：

Transplantation; Pediatric Transplantation; Immunosuppression; DOSE CYCLOSPORINE MONOTHERAPY; HEMOLYTIC-UREMIC SYNDROME; IMPROVED RENAL-FUNCTION; MYCOPHENOLATE-MOFETIL; CALCINEURIN INHIBITOR; LIVER-TRANSPLANTATION; KIDNEY-TRANSPLANTATION; MULTICENTER TRIAL; RANDOMIZED-TRIAL; CAMPATH; 1H;

D O I：

10.6061/clinics/2014(Sup01)03

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Immunosuppressive therapy in pediatrics continues to evolve. Over the past decade, newer immunosuppressive agents have been introduced into adult and pediatric transplant patients with the goal of improving patient and allograft survival. Unfortunately, large-scale randomized clinical trials are not commonly performed in children. The purpose of this review is to discuss the newer immunosuppressive agents available for induction therapy, maintenance immunosuppression, and the treatment of rejection.

引用

页码：8 / 16

页数：9

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