Preparation of aminals in water

被引：34

作者：

Jurcik, V ^{[1
]}

Wilhelm, R ^{[1
]}

机构：

[1] Tech Univ Clausthal, Inst Organ Chem, D-38678 Clausthal Zellerfeld, Germany

来源：

TETRAHEDRON | 2004年 / 60卷 / 14期

关键词：

aminals; water; solvent; imidazolidines; protecting group;

D O I：

10.1016/j.tet.2004.02.021

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Aminals, which are used as protecting groups in syntheses and are part of many biologically active compounds, are normally prepared from aldehydes and diamines under conditions that remove water in order to shift the equilibrium to the side of the aminal. Here we report for the first time that aminals can be prepared and isolated in pure water without a catalyst in high yield and purity. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：3205 / 3210

页数：6

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