A formal total synthesis of deoxybouvardin

被引：22
作者：
Bigot, A [1 ]
Beugelmans, R [1 ]
Zhu, JP [1 ]
机构：
[1] CNRS,INST CHIM SUBST NAT,F-91198 GIF SUR YVETTE,FRANCE
来源：
TETRAHEDRON | 1997年 / 53卷 / 31期
关键词：
D O I：
10.1016/S0040-4020(97)00706-0
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A synthesis of (L, L)-N, N-dimethylcycloisodityrosine 4 based on intramolecular SNAr reaction is reported. A possible explanation was proposed to account for the facile epimerization encountered in the cycloetherification of dipeptide (L,L)-10 and a solution to this problem led to a formal total synthesis of deoxybouvardin. (C) 1997 Elsevier Science Ltd.
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页码：10753 / 10764
页数：12
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